Application of cold knife conization, transvaginal cone-resection of cervix uteri and hysteroscopic coagulation adjuvant cold knife conization in high-grade squamous intraepithelial lesion
ZENG Qiu-ping LI Xiao-xia CHEN Qiao-feng
Department of Obstetrics and Gynecology, Family Planning Service Center of Maternity and Child Care Centers of Xingning City in Guangdong Province, Xingning 514500, China
Abstract：Objective To investigate the application of cold knife conization (CKC), transvaginal cone-resection of cervix uteri (TCRC) and hysteroscopic coagulation adjuvant cold knife conization (HCKC) in high-grade squamous intraepithelial lesion(HSIL).Methods The clinical data of 118 patients with HSIL who underwent surgical treatment in our hospital from January 2016 to August 2018 were retrospectively analyzed, and they were divided into the CKC group(38 cases), the TCRC group (46 cases) and the HCKC group (32 cases) according to different surgical methods. The CKC group was treated with CKC, the TCRC group was treated with TCRC, and the HCKC group was treated with HCKC.The clinical efficacy, perioperative conditions, the coincidence rate of pathological diagnosis and the total incidence of complications were compared among the three groups. Results There were no statistically significant differences between the three groups in lesion clearance rates and length of stay (P＞0.05). The operation time of the HCKC group and the TCRC group was shorter than that of the CKC group, and the intraoperative blood loss of the HCKC group and the TCRC group was less than that of the CKC group, the differences were statistically significant (P＜0.05). There was no significant difference in hospitalization time among the three groups (P＞0.05). There was statistically significant difference among the three groups in pathological diagnosis (P＜0.05). There were no significant differences in the total incidence of postoperative bleeding, cervical stenosis, abnormal menstruation, repeated abdominal pain and other complications among the three groups (P＞0.05). Conclusion CKC, TCRC and HCKC are all effective treatment methods for HSIL patients. HCKC has the advantages of short operative time, low intraoperative blood loss and high coincidence rate of pathological diagnosis, which is worthy of further promotion.
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