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中国当代医药  2020, Vol. 27 Issue (33): 80-82    
  神经与精神疾病 本期目录 | 过刊浏览 | 高级检索 |
阿司匹林结合氯吡格雷治疗脑梗死的临床效果
吴 希
辽宁省健康产业集团铁煤总医院神经内三科,辽宁调兵山 112700
Clinical effect of Aspirin combined with Clopidogrel in the treatment of cerebral infarction
WU Xi
The Third Department of Neurology,Iron and Coal General Hospital of Liaoning Health Industry Group,Liaoning Province,Diaobingshan 112700,China
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摘要 目的 研究阿司匹林结合氯吡格雷治疗脑梗死的临床效果。方法 选取2018年1月~2019年12月在辽宁省健康产业集团铁煤总医院就诊的100例脑梗死患者,采用随机数字表法分为对照组与观察组,各50例。对照组采用阿司匹林治疗,观察组采用阿司匹林结合氯吡格雷治疗。比较两组患者的神经功能缺失评分、日常生活能力、认知能力以及治疗总有效率。结果 观察组患者的治疗总有效率为92%,高于对照组的72%,差异有统计学意义(P<0.05)。观察组患者治疗后的神经功能缺失评分低于对照组,差异有统计学意义(P<0.05)。观察组患者治疗后的认知功能评分高于对照组,差异有统计学意义(P<0.05)。观察组患者治疗后的日常生活能力评分高于对照组,差异有统计学意义(P<0.05)。结论 采用阿司匹林结合氯吡格雷治疗脑梗死患者能够有效提高治疗总有效率,改善患者的认知能力、神经功能和日常生活能力,具有重要的临床研究价值。
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吴 希
关键词 阿司匹林氯吡格雷脑梗死临床效果    
AbstractObjective To study the clinical effect of Aspirin combined with Clopidogrel in the treatment of cerebral infarction.Methods A total of 100 patients with cerebral infarction in Iron and Coal General Hospital of Liaoning Health Industry Group from January 2018 to December 2019 were selected,and divided into the control group and the observation group according to random number table method,50 patients in each group.The control group was treated with Aspirin,the observation group was treated with Aspirin and Clopidogrel.The neurological deficit score,daily living ability,cognitive ability,and the total treatment effectiveness were compared between the two groups.Results The total treatment efficiency of the observation group was 92%,which was higher than 72% of the control group,the difference was statistically significant (P<0.05).The neurological deficit score of the observation group after treatment was lower than that of the control group,the difference was statistically significant (P<0.05).The cognitive function score of the observation group after treatment was higher than that of the control group,the difference was statistically significant(P<0.05).The score of daily life ability in the observation group after treatment was higher than that in the control group,the difference was statistically significant (P<0.05).Conclusion Aspirin combined with Clopidogrel in the treatment of patients with cerebral infarction can effectively improve the total effective rate,improve the cognitive ability,neurological function and daily living ability of patients,which has important clinical research value.
Key wordsAspirin    Clopidogrel    Cerebral infarction    Clinical effect
    
引用本文:   
吴 希. 阿司匹林结合氯吡格雷治疗脑梗死的临床效果[J]. 中国当代医药, 2020, 27(33): 80-82.
WU Xi. Clinical effect of Aspirin combined with Clopidogrel in the treatment of cerebral infarction. 中国当代医药, 2020, 27(33): 80-82.
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