Abstract:Objective To investigate the efficacy and safety of umbilical vein catheterization(UVC)for premature and low birth weight infants.Methods From July 2018 to October 2021,50 cases of premature and low birth weight infants admitted to Yunfu Maternal and Child Health Hospital in Guangdong Province were selected as the research objects.They were divided into the observation group and the control group by random number table method,with 25 cases in each group.The control group received conventional peripheral central venous catheterization(PICC)support treatment,and the observation group received UVC support treatment.The changes of nutritional indexes,the success rate of onetime puncture,the rate of unplanned extubation,the weight gain and the depth of catheterization in the two groups were compared before and after treatment,and the incidence of adverse events in the two groups were counted.Results The plasma albumin level of the two groups after treatment were higher than those before treatment,and the plasma albumin level of the observation group after treatment was higher than that of the control group,the differences were statistically significant(P<0.05).The success rate of one-time puncture and weight gain in the observation group after treatment were higher than those in the control group,and the unplanned extubation rate,depth of catheterization and the incidence of adverse events in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion The implementation of UVC support treatment for premature and low birth weight infants can effectively improve the treatment effect and promote the recovery of signs,and the risk of adverse events caused by UVC is lower.Compared with conventional PICC,its effectiveness and safety are higher.