Abstract：Objective To explore the application value of multi-slice spiral computed tomography (CT) in the diagnosis and treatment follow-up of non-tuberculous mycobacterial lung disease. Methods Eighty patients with suspected nontuberculous mycobacterial lung disease admitted to Ganzhou Fifth People′s Hospital from February 2019 to August 2020 were selected as the research subjects. All subjects received conventional CT examination and multi-slice spiral CT. Using pathological results as the gold standard, the detection rate, detection of different signs, diagnostic efficacy and follow-up results of the two examination methods were compared. Results The detection rate of multi-slice spiral CT was higher than that of conventional CT, and the difference was statistically significant (P<0.05). The detection rate of upper lobe cavity type, nodular bronchiectasis type, mixed type, and difficult to be classified by multi-slice spiral CT were higher than those of conventional CT, and the differences were statistically significant (P<0.05). The diagnostic sensitivity and accuracy of multi-slice spiral CT were higher than those of conventional CT, and the differences were statistically significant (P<0.05). The specificity of the two inspection methods was compared, and the difference was not statistically significant (P>0.05). Followed up for six months, a total of 24 patients showed no obvious changes in multi-slice spiral CT images, a total of 18 patients improved, the patch shadow area was reduced and the number was reduced, the cavity was reduced, the tree-in-bud sign and nodular shadow were reduced, and the patch shadow area was reduced in 28 patients. Enlarged and increased number, tree-in-bud sign and nodular shadows increased, of which 9 cases of cavities were reduced, and 19 cases of nodules and patchy shadows evolved into cavities. Conclusion Multislice spiral CT has a significant effect in the diagnosis of non-tuberculous mycobacterial pulmonary disease. It can judge different signs more accurately, improve the clinical detection rate, and has high diagnostic sensitivity. It plays an important role in the follow-up evaluation of treatment. It is recommended to be promoted use.
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