龙血竭粉溶解液注射医用膨胀海绵对鼻内镜下慢性鼻窦炎鼻息肉切除术后患者的止血效果

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摘要目的评估龙血竭粉溶解液注射医用膨胀海绵对鼻内镜下慢性鼻窦炎鼻息肉切除术后患者的止血效果。方法选取2014年10月至2021年5月于江西省中西医结合医院行鼻内镜治疗的40 例双侧慢性鼻窦炎鼻息肉切除术后住院患者作为研究对象，采用随机数字表法将其分为观察组和对照组，每组各20 例。观察组患者应用龙血竭粉溶解液注射医用膨胀海绵填塞止血，对照组患者则应用0.9%生理盐水注射医用膨胀海绵填塞止血。观察比较两组患者的术后鼻部止血疗效、鼻腔黏膜愈合情况。结果观察组患者的术后止血总有效率高于对照组，差异有统计学意义（P<0.05）。两组患者治疗前的各项症状、体征积分比较，差异无统计学意义（P>0.05）。观察组患者治疗后的治疗症状及体征改善情况优于对照组，差异有统计学意义（P<0.05）。两组患者治疗后的术后出血量、出血次数、鼻塞、头昏、鼻黏膜、分泌物、息肉、瘢痕、结痂评分及总评分低于本组治疗前，差异有统计学意义（P<0.05）。观察组患者治疗后的术后出血量、出血次数、鼻塞、头昏、鼻黏膜、分泌物、息肉评分及总评分低于对照组，差异有统计学意义（P<0.05）。两组患者治疗后的瘢痕、结痂评分比较，差异无统计学意义（P>0.05）。结论在鼻内镜下慢性鼻窦炎鼻息肉切除术后，鼻腔应用龙血竭粉溶解液注射医用膨胀海绵填塞止血具有较高的临床价值，且术后鼻腔黏膜愈合较好，值得临床应用及推广。

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关键词 ：鼻内镜手术, 龙血竭粉溶解液, 慢性鼻窦炎鼻息肉, 止血效果

Abstract：Objective To evaluate the hemostatic effect of injecting Longxuejie Powder dissolving solution into medical swelling sponge on patients of chronic sinusitis with nasal polyps resection under nasal endoscopy. Methods From October 2014 to May 2021, 40 patients of bilateral chronic sinusitis with nasal polyps resection under nasal endoscopy who were treated in Jiangxi Province Hospital of Chinese and Western Combination were used as research subjects.They were divided into observation group and control group by random number table method, 20 cases in each group.Observation group was treated with injecting Longxuejie Powder dissolving solution into medical swelling sponge for hemostasis. Patients in control group were treated with 0.9% normal saline injection of medical expandable sponge for hemostasis. The curative effect of nasal hemostasis and nasal mucosahealing were observed and compared between the two groups. Results The total effective rate of hemostasis in the observation group was higher than that in the control group, and the difference was statistically significant (P<0.05). There was no significant difference in the scores of symptoms and signs between the two groups before treatment (P>0.05). The improvement of symptoms and signs in the observation group was better than that in the control group after treatment, and the difference was statistically significant (P<0.05). After treatment, the amount and frequency of bleeding, nasal congestion, dizziness, nasal mucosa, secretions, polyps, scars, scabs scores and total scores of the two groups were lower than those before treatment, and the differences were statistically significant (P<0.05). The scores of amount and frequency of bleeding, nasal congestion, dizziness, nasal mucosa, secretions and polyps in the observation group were lower than those in the control group after treatment, and the differences were statistically significant (P<0.05). However, there were no significant differences between the two groups in the scores of changes in scars and scabs after treatment (P>0.05). Conclusion After polyps resection of chronic sinusitis under nasal endoscopy, nasal injection of Longxuejie Powder dissolving solution for medical expansion and packing to stop bleeding has high clinical value, and the postoperative nasal mucosa healed well, which is worthy of clinical application and promotion.

Key words： Endoscopic sinus surgery Longxuejie Powder dissolving solution Chronic sinusitis with nasal polyps;Hemostatic effect

基金资助:江西省卫生厅中医药科研基金（2010B007）

引用本文:

吴伟琨；操建；熊美华；万金华；付欢欢. 龙血竭粉溶解液注射医用膨胀海绵对鼻内镜下慢性鼻窦炎鼻息肉切除术后患者的止血效果[J]. 中国当代医药, 2022, 29(8): 11-14转20.
WU Weikun CAO Jian XIONG Meihua WAN Jinhua FU Huanhuan. Hemostatic effect of injecting Longxuejie Powder dissolving solution into medical swelling sponge on patients of chronic sinusitis with nasal polyps resection under nasal endoscopy. 中国当代医药, 2022, 29(8): 11-14转20.

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