阻抗运动在青年冠心病PCI术后患者中的应用及对心功能及炎症因子表达的影响

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摘要目的探索阻抗运动对青年冠心病经皮冠状动脉介入（PCI）术后患者心功能及炎症因子表达的影响。方法选取2016年1月～2018年2月于我院成功施行PCI 术的40 例青年冠心病患者作为研究对象，采用完全随机分组方法分为实验组和对照组，每组各20 例。实验组患者在常规预防用药基础上予阻抗运动，对照组患者予常规预防用药。在治疗前及治疗1年后测量两组患者的运动代谢当量（MET）、左室射血分数（LVEF）、峰值功率（Pp）、白介素-6（IL-6）及白介素-10（IL-10）浓度。结果治疗1年后，实验组患者的MET、LVEF、Pp 均高于对照组，差异有统计学意义（P＜0.05）；实验组患者的IL-6 浓度低于对照组，IL-10 浓度高于对照组，差异有统计学意义（P＜0.05）。结论阻抗运动治疗1年后可显著改善青年冠心病PCI 术后患者的心脏功能及减少炎症反应，从而改善疾病预后。

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	罗丽雯

关键词 ：阻抗运动, 经皮冠状动脉介入术, 心功能, 炎症因子

Abstract：Objective To investigate the application of impedance exercise in young patients with coronary heart disease after percutaneous coronary intervention (PCI) therapy and its effect on cardiac function and expression of inflammatory factors. Methods A total of 40 young coronary heart disease patients received PCI in our hospital from January 2016 to February 2018 were selected as the study objects and divided into the experimental group and the control group by completely random grouping method, with 20 cases in each group. Patients in the experimental group were given impedance exercise on the basis of routine prophylactic medication, while patients in the control group were given routine prophylactic medication. Exercise equivalent (MET), left ventricular ejection fraction (LVEF), peak power(Pp), and interleukin-6 (IL-6), interleukin-10 (IL-10) concentrations were compared at the beginning of the treatment and after 1 year of treatment. Results After 1 year of treatment, the MET, LVEF and Pp of the experimental group were higher than those of the control group, and the differences were statistically significant (P＜0.05). The IL-6 concentration in the experimental group was lower than that of the control group, the IL-10 concentration was higher than that of the control group, and the differences were statistically significant (P＜0.05). Conclusion Impedance exercises can enhance cardiac function of young coronary heart disease patients receiving PCI therapy and reduce inflammatory response, than improve the prognosis of the disease.

Key words： Impedance exercises Percutaneous coronary intervention Cardiac function Inflammatory cytokine

引用本文:

罗丽雯. 阻抗运动在青年冠心病PCI术后患者中的应用及对心功能及炎症因子表达的影响[J]. 中国当代医药, 2020, 27(28): 58-61.
LUO Li-wen. Application of impedance exercise in young patients with coronary heart disease after PCI and its effect on cardiac function and expression of inflammatory factors. 中国当代医药, 2020, 27(28): 58-61.

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