Abstract:Objective To explore the clinical effect of Lemon Essential Oil on the prevention of respiratory tract infections after abdominal tracheal intubation under general anesthesia.Methods A total of 408 patients undergoing abdominal gynecological surgery under elective intubation under general anesthesia in the First People′s Hospital of Changde City from April 2020 to December 2020 were selected as the research objects,they were divided into the Milian Pei Pa Koa group (136 cases),Lemon Essential Oil sublingual group (137 cases),Lemon Essential Oil spray group (135 cases) by using a random number table methods.The Milian Pei Pa Koa group was given Milian Pei Pa Koa containing,and the Lemon Essential Oil sublingual group was given the diluted Lemon Essential Oil containing,and the Lemon Essential Oil spray group was given the diluted Lemon Essential Oil spraying.The protective effect of respiratory tract infections after abdominal tracheal intubation under general anesthesia,relief of respiratory symptoms,pathogenic bacteria types and colony counts of respiratory secretions among the three groups of patients were compared.Results The protective effect of respiratory tract infections after abdominal tracheal intubation under general anesthesia of the Lemon Essential Oil sublingual group and the Lemon Essential Oil spray group were higher than those of the Milian Pei Pa Koa group,and the differences were statistically significant (P<0.017).The relief of symptoms of throat discomfort on the 2nd,the 3rd and the 4th day of preventive treatment in the Lemon Essential Oil sublingual group were better than those in the the Milian Pei Pa Koa group,the relief of symptoms of cough and sputum,cough difficulty on the 3rd and the 4th day of preventive treatment in the Lemon Essential Oil sublingual group were better than those in the Milian Pei Pa Koa group,with statistical significance (P<0.017).The relief of symptoms of throat discomfort on the 3rd and the 4th day of preventive treatment in the Lemon Essential Oil spray group were better than those in the Milian Pei Pa Koa group,the relief of symptoms of cough and sputum,cough difficulty on the 4th day of preventive treatment in the Lemon Essential Oil spray group were better than those in the Milian Pei Pa Koa group,with statistical significance (P<0.017).The count of pathogenic bacteria in respiratory secretions after preventive treatment in the Lemon Essential Oil sublingual group and the Lemon Essential Oil spray group were lower than those in the Milian Pei Pa Koa group,with statistical significance(P<0.05).There were no significant differences in protective effect of respiratory tract infections after abdominal tracheal intubation under general anesthesia,respiratory symptom relief,pathogenic bacteria species and colony count in respiratory secretions between the Lemon Essential Oil sublingual group and the Lemon Essential Oil spray group (P>0.05).Conclusion Both Lemon Essential Oil sublingual and spray can effectively prevent respiratory tract infections after abdominal tracheal intubation under general anesthesia and significantly improve symptoms of respiratory tract infections.
Beeh KM,Beier J,Candler H,et al.Effect of ELOM-080 on exacerbations and symptoms in COPD patients with a chronic bronchitis phenotype-a post-hoc analysis of a randomized,double-blind,placebo-controlled clinical trial[J].Int J Chron Obstruct Pulmon Dis,2016,23(11):2887-2884.
[20]
Fürst R,Luong B,Thomsen J,et al.ELOM-080 as add-on treatment for respiratory tract diseases-a review of clinical studies conducted in China[J].Planta Med,2019,85(90):745-754.