Clinical characteristics and risk factors of acute myocardial infarction with new atrial fibrillation
CHEN Shuo LI Peng FANG Meng XU Jianhui
The Second Department of Cardiology,Xiaogan Hospital Affiliated to Wuhan University of Science and Technology,Xiaogan Central Hospital,Hubei Province,Xiaogan 432000,China
Abstract:Objective To analyze the clinical characteristics and risk factors of patients with acute myocardial infarction(AMI) with new-onset atrial fibrillation (NOAF).Methods A total of 230 patients with AMI admitted to Xiaogan Central Hospital from May 2021 to February 2022 were selected as the study objects.According to the occurrence of NOAF after AMI,the patients were divided into study group (25 cases in NOAF group) and control group (205 cases in without NOAF).Clinical characteristics of the two groups,such as age,gender,smoking history and hypertension history,were collected.The results of laboratory tests,such as cardiac troponin I (CTNI),brain natriuretic peptide (BNP),C-reactive protein(CRP),the ratio of CRP to serum albumin (CRA),etc.were collected.The results of imaging examinations including left atrial end-diastolic diameter (LAED) and left ventricular end-diastolic dimension (LVEDD) were collected.Multivariate logistic regression was used to analyze the risk factors of NOAF after AMI.Results Univariate analysis showed that there were statistically significant differences in the proportion of hypertension history,BNP,KILLIP grade,CRP,CRA and LAED between NOAF group and control group,and the differences were statistically significant (P<0.05).Multivariate analysis results indicated that BNP (β=1.423,OR=4.148,95%CI: 1.139~15.099),KILLIP ≥grade Ⅱ(β=1.707,OR=5.515,95%CI:1.017~29.903),CRP (β=2.096,OR=8.132,95%CI:1.541~42.895),CRA (β=2.212,OR=9.136,95% CI:1.159~72.024),LAED (β=2.472,OR=11.851,95%CI:2.571~54.619) were the risk factors for NOAF after AMI(P<0.05,OR>1).Conclusion BNP,KILLIP grade≥Ⅱ,CRP,CRA and LAED are risk factors for AMI with NOAF.