Effect evaluation of Shuxuetong Injection in the treatment of ischemic stroke
DENG Yongxiong1 BI Haiquan2
1.Department of Internal Medicine,Yongchuan Huimin Traditional Chinese Medicine Hospital,Chongqing 402171,China;
2.General Ward,the First Affiliated Hospital of Chongqing Medical and Pharmaceutical College,Chongqing 402160,China
Abstract：Objective To explore the effect of Shuxuetong Injection in the treatment of ischemic stroke.Methods From January 2019 to May 2023,a total of 49 patients with ischemic stroke in Yongchuan Huimin Traditional Chinese Medicine Hospital of Chongqing City were selected as the research objects,and they were divided into control group (24 cases) and observation group (25 cases) according to random number table method.The control group were treated with Aspirin and Clopidogrel,while the observation group were treated with Shuxuetong Injection on the basis of the treatment of the control group.The clinical efficacy and the incidence of bleeding during treatment were compared between the two groups,and the coagulation function and disease-related scores before and after treatment were compared between the two groups.Results After treatment,the total effective rate of the observation group was higher than that of the control group,and the total incidence of bleeding was lower than that of the control group,and the differences were statistically significant (P＜0.05).After treatment,the activated partial thromboplastin time (APTT)and prothrombin time (PT)of the two groups were longer than those before treatment,the international normalized ratio (INR) and Barthel index (BI) score of the two groups were higher than those before treatment,the D-dimer(D-D)level,the national institutes of health stroke scale(NIHSS)score and the traditional Chinese medicine symptom score of the two groups were lower than those before treatment,and the differences were statistically significant (P＜0.05).After treatment,the APTT and PT of the observation group were longer than those of the control group,the INR value and BI score of the observation group were higher than those of the control group,and the D-D level,the NIHSS score and the traditional Chinese medicine symptom score of the observation group were lower than those of the control group,and the differences were statistically significant(P＜0.05).Conclusion Shuxuetong Injection can effectively improve the clinical efficacy,improve the coagulation function and neurological function,reduce the incidence of bleeding and improve the daily living ability of patients.
邓永雄1； 毕海权2. 疏血通注射液治疗缺血性脑卒中的效果评价[J]. 中国当代医药, 2024, 31(13): 15-18转23.
DENG Yongxiong1 BI Haiquan2. Effect evaluation of Shuxuetong Injection in the treatment of ischemic stroke. 中国当代医药, 2024, 31(13): 15-18转23.
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