Analysis of influencing factors of chronic hepatitis B combined with depression
LIN Wenqing1 XIE Weining2
1.School of Public Health and Management,Guangzhou University of Chinese Medicine,Guangdong Province,Guangzhou 510006,China;
2.Department of Infectious Disease,Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine,Guangdong Province,Foshan 510632,China
Abstract：Objective To investigate the influencing factors of chronic hepatitis B combined with depression.Methods A population of chronic hepatitis B patients who admitted to the Department of Infectious Disease of Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine from January 2022 to January 2023 were selected as the research subjects.By using a questionnaire survey,general information such as age,gender,weight,marital status,smoking and drinking history,education status,as well as traditional Chinese medicine constitution analysis,traditional Chinese medicine syndrome analysis and depression score were collected.Use logistic regression to analyze the influencing factors of chronic hepatitis B complicated with depression.Results A total of 365 patients were ultimately included in the study,including 96 patients with depression and 299 patients without depression.The results of univariate analysis showed that there were statistically significant differences in the comparison of depression among different types of traditional Chinese medicine constitution,traditional Chinese medicine syndrome differentiation and family history of depression(P＜0.05).The results of multivariate logistic regression analysis showed that Qi stagnation(OR=5.579,95%CI:2.063-15.087),blood stasis(OR=5.590,95%CI: 2.09-15.553),liver depression and spleen deficiency (OR=4.875,95%CI: 1.696-14.013),liver depression and phlegm obstruction (OR=6.515,95%CI:2.343-18.119),liver stagnation and Qi stagnation (OR=4.282,95%CI: 1.555-11.791)and family history of depression(OR=18.847,95%CI:5.416-65.584)were independent risk factors for chronic hepatitis B complicated with depression (P＜0.05).Conclusion Family history of depression,Qi stagnation,blood stasis,liver stagnation and spleen deficiency,liver stagnation and phlegm obstruction,liver stagnation and Qi stagnation are independent risk factors for chronic hepatitis B complicated with depression.It is necessary to pay attention to these high-risk factors in clinical practice and provide certain reference value for clinical intervention.
林文清；谢维宁. 慢性乙型肝炎合并抑郁症的影响因素分析[J]. 中国当代医药, 2023, 30(21): 105-109.
LIN Wenqing1 XIE Weining2. Analysis of influencing factors of chronic hepatitis B combined with depression. 中国当代医药, 2023, 30(21): 105-109.
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