冠状动脉造影前后肾段动脉超声血流参数变化及影响因素

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摘要目的探究冠状动脉造影前后肾段动脉超声血流参数变化及影响因素。方法选取2020年7月至2021年4月西安市第九医院拟行冠状动脉造影或经皮冠状动脉介入治疗（PCI）的46 例患者为研究对象，于造影前、造影后第3、10 天分别测量患者双侧肾段动脉的收缩期峰值流速（PSV）、舒张末期流速（EDV）、阻力指数（RI），并用多元线性回归分析影响肾血流参数的因素。结果造影后第3、10 天PSV 高于造影前，造影后第10 天EDV 高于造影前及造影后第3 天，造影后第3 天RI 高于造影前，差异有统计学意义（P＜0.05）。造影后第3 天，PSV 与年龄及性别相关，EDV 与年龄及钙通道阻滞剂（CCB）的使用相关；而造影后第10 天，PSV 仅与年龄相关，EDV 与年龄、造影剂量及体重指数相关；造影后第3、10 天RI 均与年龄及糖尿病相关。结论冠脉造影后肾段动脉PSV、EDV、RI造影后呈现出先恶化后改善的趋势。造影后PSV 受年龄及性别的影响，EDV 受年龄、CCB、造影剂量及体重指数影响，RI 受年龄及糖尿病影响。其中，年龄是肾血流参数最显著的影响因素，与造影剂本身无关。

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	黄霜
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关键词 ：冠脉造影, 超声肾血流参数, 肾损伤, 肾阻力指数

Abstract：Objective To investigate the influencing factors and the changes of ultrasonic blood flow parameters of renal segmental artery before and after coronary angiography. Methods A total of 46 patients undergoing coronary angiography or percutaneous coronary intervention (PCI) in Ninth Hospital of Xi′an from July 2020 to April 2021 were selected as the study subjects. The peak systolic velocity (PSV),end diastolic velocity (EDV)and resistance index (RI) of bilateral renal segmental arteries were measured before angiography and the 3rd day and the 10th day after angiography.The influencing factors of renal blood flow parameters after radiography were also discussed by multiple linear regression analysis. Results The PSV on the 3rd day and 10th day after angiography were higher than that before angiography,the EDV on the 10th day after angiography was higher than that before angiography and on the 3rd day after angiography,the RI on the 3rd day after angiography was higher than that before angiography, the differences were statistically significant (P＜0.05). On the 3rd day after angiography, PSV was related to age and gender, EDV was correlated with age and the using of Calcium Channel Blockers (CCB). While on the 10th day after angiography, PSV was only related to age,EDV was correlated with age, the dose of contrast medium and body mass index. On the 3rd day and 10th day after angiography, RI was related to age and diabetes. Conclusion PSV, EDV and RI of segmental renal arteries show a trend of deterioration and subsequent improvement. After angiography, age and gender are the influencing factors of PSV.Age, CCB, contrast agent volume and body mass index are the influencing factors of EDV, then age and diabetes are the influencing factors of RI. Among them, age is the most significant influencing factor for renal blood flow parameters, regardless of the contrast agent itself.

Key words： Coronary angiography Ultrasonic renal blood flow parameters Renal function damage Resistance index

基金资助:国家自然科学基金资助项目（81673787）；陕西省西安市科技计划项目[2019114613YX001SF036（3）]

通讯作者: 郝霁萍（1975-），女，硕士，超声医学科主任，副主任医师，硕士生导师。

作者简介: 黄霜（1997-），女，西安医学院2019 级影像医学与核医学超声方向在读硕士研究生。

引用本文:

黄霜；郝霁萍；高宇勤；梁欧婧；田丰. 冠状动脉造影前后肾段动脉超声血流参数变化及影响因素[J]. 中国当代医药, 2022, 29(8): 125-129.
HUANG Shuang； HAO Jiping； GAO Yuqin； LIANG Oujing；TIAN Feng. Changes and influencing factors of ultrasonic blood flow parameters of renal segmental artery before and after coronary angiography. 中国当代医药, 2022, 29(8): 125-129.

链接本文:

https://www.dangdaiyiyao.com/CN/ 或 https://www.dangdaiyiyao.com/CN/Y2022/V29/I8/125

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