Application effect of probiotics in hemodialysis patients
WANG Fuzhen1 SONG Maoqing2 WANG Kun2 LI Guirong2 ZHONG Shaorong1▲ ZHANG Yu1 DENG Jinxiu
1.Department of Nephrology,the First Affiliated Longyan Hospital of Fujian Medical University,Fujian Province,Longyan 364000,China;
2.Xiamen Yilikang Biotechnology Co.,Ltd.,Fujian Province,Xiamen 361000,China
Abstract：Objective To study the application effect of probiotics in hemodialysis patients.Methods A total of 156 patients who underwent hemodialysis in the First Affiliated Longyan Hospital of Fujian Medical University from April 1 to May 1,2020 were selected as research subjects.According to the different intervention methods,they were divided into experimental group (104 cases,oral administration of superior bacteria 80 probiotics) and control group (52 cases,oral administration of control agent without bacterial strains).The levels of hemoglobin (Hb),albumin (ALB) and parathyroid hormone(PTH)before intervention and 30 and 60 days after intervention were compared between the two groups.The levels of T lymphocytes and β2 microglobulin were compared between the two groups before intervention and 30 and 60 days after intervention.Results After 30 and 60 days of intervention,the levels of Hb and ALB in the experimental group were higher than those in the control group,and the levels of PTH in the experimental group were lower than those in the control group,and the differences were statistically significant(P＜0.05).After 60 days of intervention,the levels of T lymphocytes and β2 microglobulin in the experimental group were lower than those in the control group,and the differences were statistically significant (P＜0.05).Conclusion Probiotics have a certain effect on improving nutrition and inflammation in HD patients,and the effect is more significant with the prolonged time of taking probiotics.
王福珍；宋茂清； 王坤；李贵荣；钟少榕； 章宇； 邓金秀. 益生剂在血液透析患者中的应用效果[J]. 中国当代医药, 2022, 29(31): 112-116.
WANG Fuzhen1 SONG Maoqing2 WANG Kun2 LI Guirong2 ZHONG Shaorong1▲ ZHANG Yu1 DENG Jinxiu. Application effect of probiotics in hemodialysis patients. 中国当代医药, 2022, 29(31): 112-116.
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