Abstract:Objective To explore the clinical effects of Clopidogrel and Ticagrelor in the treatment of acute myocardial infarction.Methods Eighty patients with acute myocardial infarction who underwent percutaneous coronary intervention(PCI) admitted to the Iron Coal General Hospital of Liaoning Health Industry Group from January 2019 to January 2020 were selected as the research subjects.They were divided into observation group and control group according to random number table method,with 40 cases in each group.The patients in the observation group were treated with Ticagrelor and the patients in the control group were treated with Clopidogrel.The platelet count,platelet aggregation rate,maximum aggregation time of adenosine diphosphate(ADP),maximum aggregation rate of ADP,cardiac function and total incidence of complications of two groups were compared.Results The platelet count and platelet aggregation rate in the observation group after treatment were lower than those in the control group,while the maximum aggregation time of ADP was longer than that in the control group,the maximum aggregation rate of ADP was higher than that in the control group,the differences were statistically significant (P<0.05).After treatment,the cardiac function of the two groups was better than that before treatment,and the cardiac function of the observation group was better than that of the control group,the differences were statistically significant (P<0.05).The total incidence of complications of patients during the treatment period in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion Compared with Clopidogrel,Ticagrelor has a better clinical effect in the treatment of acute myocardial infarction.It can improve the cardiac function of patients with high safety,and is worthy of promotion.
焦祺. 氯吡格雷与替格瑞洛治疗急性心肌梗死的临床效果比较[J]. 中国当代医药, 2022, 29(3): 74-77.
JIAO Qi. Comparison of the clinical effect of Clopidogrel and Ticagrelor in the treatment of acute myocardial infarction. 中国当代医药, 2022, 29(3): 74-77.