呼吸功能锻炼联合特布他林雾化治疗老年慢性阻塞性肺疾病急性加重期患者的临床效果

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摘要目的探讨呼吸功能锻炼联合特布他林雾化治疗慢性阻塞性肺疾病急性加重期（AECOPD）患者的疗效。方法选取2020年8月至2021年8月赣州市人民医院收治的86 例老年AECOPD 患者作为研究对象，采用随机投掷法分为对照组（43 例）和观察组（43 例）。对照组采用特布他林雾化＋常规治疗，观察组采用呼吸功能锻炼联合特布他林雾化＋常规治疗，比较两组的治疗效果。结果观察组总有效率高于对照组，且观察组治疗后呼吸困难评估量表问卷分级优于对照组，差异有统计学意义（P＜0.05）。治疗后，观察组动脉血氧分压（PaO2）高于对照组，动脉血二氧化碳分压（PaCO2）、C 反应蛋白（CRP）水平均低于对照组，差异有统计学意义（P＜0.05）。两组不良反应总发生率比较，差异无统计学意义（P＞0.05）。结论老年AECOPD 患者采用呼吸功能锻炼联合特布他林雾化进行治疗可有效改善血气指标，提升总有效率，降低症状评分，且无严重不良反应。

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关键词 ：呼吸功能锻炼, 特布他林雾化, 慢性阻塞性肺疾病, 急性加重期

Abstract：Objective To investigate the efficacy of respiratory function exercise combined with Terbutaline nebulization in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods A total of 86 elderly patients with AECOPD who were admitted to Ganzhou People's Hospital during the period from August 2020 to August 2021 were selected as the research subjects.According to the random throwing method,the control group (43 cases) and the observation group (43 cases).The control group were given Terbutaline atomization ＋conventional treatment.The observation group were given respiratory function exercise combined with Terbutaline atomization＋conventional treatment.The treatment effects of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group,and the modified Medical Research Council scale questionnaire grading performance of the observation group after treatment was better than that of the control group,and the differences were statistically significant (P＜0.05).After treatment,the arterial oxygen partial pressure (PaO2) in the observation group was higher than that in the control group,the arterial carbon dioxide partial pressure (PaCO2) and Creactive protein (CRP) levels in the observation group were lower than those in the control group,and the differences were statistically significant (P＜0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion Respiratory exercise combined with Terbutaline Atomization can not only effectively improve blood gas index,improve the total effective rate,reduce symptom score,but also have no serious adverse reactions in elderly patients with AECOPD.

Key words： Respiratory function exercise Terbutaline atomization Chronic obstructive pulmonary disease Acute exacerbation

基金资助:江西省赣州市卫生健康委员会市级科研计划项目（2020-2-19）。

作者简介: 谢武明（1989-），男，汉族，江西吉安人，硕士，研究方向：肺部感染、慢性阻塞性肺疾病、胸腔积液、发热。

引用本文:

谢武明；刘媛. 呼吸功能锻炼联合特布他林雾化治疗老年慢性阻塞性肺疾病急性加重期患者的临床效果[J]. 中国当代医药, 2022, 29(28): 78-81.
XIE Wuming LIU Yuan. Clinical effect of respiratory function exercise combined with Terbutaline atomization on elderly patients with acute exacerbation of chronic obstructive pulmonary disease. 中国当代医药, 2022, 29(28): 78-81.

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