Abstract：Objective To explore the factors influencing the development of kidney stones based on the dietary inflammatory index (DII) analysis.Methods A total of 192 patients with kidney stones diagnosed with the urology center of the People's Hospital of Xinjiang Uygur Autonomous Region from August 2020 to July 2021 were selected as the stone group,and 192 participants with healthy physical examination in the People's Hospital of Xinjiang Uygur Autonomous Region during the same period were selected as the non-stone group.The gender,age,body mass index,DII score and other factors were compared between the two groups to analyze the influencing factors of kidney stone incidence.Results DII scores of all participants were 0.91 (-4.36,4.85),and the pro-inflammatory diet participants in the stone group(DII＞0.91) were more than those in the non-stone group,the difference was statistically significant (P＜0.05).The result of univariate analysis showed that there were statistically significant differences in energy intake,smoking or not,drinking or not,water intake and DII score between the stone group and the non-stone group (P＜0.05).The result of multifactorial logistic regression analysis showed that energy intake (β=0.622,OR=1.980,95%CI=1.631-5.019),body mass index＞28 kg/m2 (β=0.854,OR=2.349,95%CI=1.328-4.155) and DII score＞0.91 (β=0.544,OR=1.740,95%CI=1.126-2.687) were risk factors for the development of kidney stones.Water intake＞2 000 ml/d (β=-0.885,OR=0.413,95%CI=0.199-0.856) was protective factors for the development of kidney stones.Conclusion It is suggested that the population should adjust their diet to a low DII state,namely,anti-inflammatory diet.Meanwhile,it is suggested that the population should control their body mass index and increase their water intake to＞2 000 ml/d,which may play an important role in the prevention of kidney stones.
胡开国； 刘彼得；霍宇杰； 黄雨龙；田园；董强；李九智. 基于膳食炎症指数肾结石发病的影响因素分析[J]. 中国当代医药, 2022, 29(28): 24-27.
HU Kaiguo1 LIU Bide2 HUO Yujie2 HUANG Yulong2 TIAN Yuan2 DONG Qiang2 LI Jiuzhi. Analysis of factors influencing the development of kidney stones based on dietary inflammatory index. 中国当代医药, 2022, 29(28): 24-27.
Mulay SR，Honarpisheh MM，Foresto-Neto O，et al.Mitochondria Permeability Transition versus Necroptosis in Oxalate-Induced AKI[J].J Am Soc Nephrol，2019，30（10）：1857-1869.
[3]
Bolte LA，Vich Vila A，Imhann F，et al.Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome[J].Gut，2021，70（7）：1287-1298.
[4]
Shivappa N，Steck SE，Hurley TG，et al.Designing and developing a literature-derived，population-based dietary inflammatory index[J].Public Health Nutr，2014，17（8）：1689-1696.
[5]
Almeida-De-Souza J，Santos R，Barros R，et al.Dietary inflammatory index and inflammatory biomarkers in adolescents from LabMed physical activity study[J].Eur J Clin Nutr，2018，72（5）：710-719.
[6]
Yi Q，Li X，He Y，et al.Associations of dietary inflammatory index with metabolic syndrome and its components：a systematic review and meta-analysis[J].Public Health Nutr，2021，24（16）：5463-5470.
[7]
Shivappa N，Wirth MD，Hurley TG，et al.Association between the dietary inflammatory index（DII）and telomere length and C-reactive protein from the National Health and Nutrition Examination Survey-1999-2002[J].Mol Nutr Food Res，2017，61（4）：1-19.
Khan SR，Canales BK，Dominguez-Gutierrez PR.Randall's plaque and calcium oxalate stone formation：role for immunity and inflammation[J].Nat Rev Nephrol，2021，17（6）：417-433.
Solak V，Gokce MI，Yaman O.Potassium citrate vs.hydrochlorothiazide to reduce urinary calcium excretion in calcium oxalate stone patients with hypercalciuria：a prospective randomized study[J].Int Urol Nephrol，2021，53（9）：1791-1796.
[15]
Zhang C，Qiu S，Bian H，et al.Association between Dietary Inflammatory Index and kidney stones in US adults：data from the National Health and Nutrition Examination Survey（NHANES）2007-2016[J].Public Health Nutr，2021，24（18）：6113-6121.
[16]
Maddahi N，Yarizadeh H，Aghamir SMK，et al.The association of dietary inflammatory index with urinary risk factors of kidney stones formation in men with nephrolithiasis[J].BMC Res Notes，2020，13（1）：373-379.
[17]
Pirouzeh R，Heidarzadeh-Esfahani N，Morvaridzadeh M，et al.Effect of DASH diet on oxidative stress parameters：A systematic review and meta-analysis of randomized clinical trials[J].Diabetes Metab Syndr，2020，14（6）：2131-2138.
[18]
Rodriguez A，Curhan GC，Gambaro G，et al.Mediterranean diet adherence and risk of incident kidney stones[J].Am J Clin Nutr，2020，111（5）：1100-1106.
[19]
Turner-Mcgrievy GM，Wirth MD，Shivappa N，et al.Impact of a 12-month Inflammation Management Intervention on the Dietary Inflammatory Index，inflammation，and lipids[J].Clin Nutr ESPEN，2019，30：42-51.
[20]
Corley J，Shivappa N，Hebert JR，et al.Associations between Dietary Inflammatory Index Scores and Inflammatory Biomarkers among Older Adults in the Lothian Birth Cohort 1936 Study[J].J Nutr Health Aging，2019，23（7）：628-636.
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