Abstract：Objective To investigate the sleep apnea hypopnea index (AHI) grade in patients with obstructive sleep apnea hypopnea syndrome (OSASH) and its independent risk factors. Methods A total of 300 patients with sleep-disordered breathing admitted to the First People′s Hospital of Kashgar from July 2019 to July 2021 were selected as the research objects. According to AHI, AHI<5 times/h and polysomnography (PSG) indicated snoring were divided into simple snoring group. 5-14 times/h was considered as mild, 15-30 times/h was considered as moderate, and >30 times/h was considered as severe. All patients were divided into OSASH group. Univariate analysis was used to screen the related factors of OSASH patients, and multivariate logistic regression was used to analyze the independent risk factors of AHI classification. The factor analysis method was used to reduce the dimension of all factors, and the factors were rotated to extract the common factors. Results Among the 300 OSAHS patients, 168 were simple snoring (56.00%) and 132 were in the OSASH group (44.00%), of which 74 were mild (56.06%), 23 were moderate (17.42%), and 35 were severe (26.52%). There were significant differences in body mass index (BMI), history of hypertension, history of diabetes,neck circumference, abdominal circumference, systolic blood pressure, diastolic blood pressure, Epworth sleeping scale(ESS), AHI, frequency of apnea or hypopnea, and cumulative time of apnea or hypopnea between simple snoring group and OSASH group (P<0.05). There were statistically significant differences in BMI, ESS, AHI, times of apnea or hypopnea, cumulative time of apnea or hypopnea, and blood oxygen saturation in patients with different degrees of OSAHS (P<0.05). A total of 4 independent factors with common factor variance eigenvalue ≥1 were extracted,namely PSG monitoring related indicators, cardiovascular related indicators, age and medical history, and ethnic body mass indicators. Multivariate logistic analysis showed that BMI, ESS, AHI, times of apnea or hypopnea, and cumulative time of apnea or hypopnea were risk factors for the severity of OSAHS (OR＞1, P<0.05). Conclusion BMI, ESS, AHI,the number of apnea or hypopnea, and the cumulative time of apnea or hypopnea are independent influencing factors of the severity of OSASH patients. Clinical interventions should be targeted at these factors.
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