Abstract：Objective To analyze the effect of Aspirin combined with Clopidogrel in the treatment of patients with acute cerebral infarction. Methods A total of 100 patients with acute cerebral infarction admitted to the Hongqi Hospital Affiliated to Mudanjiang Medical College from May 2019 to May 2020 were selected as the research objects, and they were divided into the reference group and the experimental group by drawing lots, with 50 cases in each group. The patients in the reference group received Aspirin. The experimental group was treated with Clopidogrel on the basis of the reference group. The therapeutic effect, the neurological function scores before and after treatment and the adverse reactions were compared between the two groups. Results The total effective rate of the experimental group was higher than that of the reference group, and the difference was statistically significant (P<0.05). Before treatment, there was no statistically significant difference in neurological function scores between the two groups (P>0.05). After 1, 5 and 10 d of treatment, the neurological function scores of the two groups were lower than those before treatment, and the differences were statistically significant (P<0.05). After 1, 5 and 10 d of treatment, the neurological function scores of the experimental group were lower than those of the reference group, and the differences were statistically significant (P<0.05). The total adverse reaction rate of the experimental group was lower than that of the reference group, and the difference was statistically significant (P<0.05). Conclusion The application of Aspirin combined with Clopidogrel in the treatment of acute cerebral infarction can improve the therapeutic effect and neurological function, and reduce the adverse reactions rate, which is worthy of clinical promotion and application.
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