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中国当代医药  2022, Vol. 29 Issue (17): 170-172转176    
  检验医学 本期目录 | 过刊浏览 | 高级检索 |
血栓弹力图与常规凝血试验在临床合理用血指导中的应用价值比较
谷瑞霖
厦门市第五医院输血科
Comparison of thromboelastogram and routine coagulation test in the guidance of clinical rational blood use
GU Ruilin
Department of Blood Transfusion,Xiamen Fifth Hospital
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摘要 目的 比较血栓弹力图(TEG)与常规凝血试验(CCT)在临床合理用血指导中的应用价值。方法 选取2020年3月至2021年3月于厦门市第五医院进行TEG 与CCT 检查的83 例有输血指征的患者作为研究对象。所有患者均进行TEG、CCT 及血小板计数(PLTs)检查。分析TEG、CCT 指标结果及两者的相关性,比较TEG 与CCT 指导血液成分输注量的应用价值。结果 83 例患者的血凝块形成时间(K)值为(3.92±1.08)min、反应时间(R)值为(10.58±4.16)min、最大振幅(MA)为(42.34±10.92)mm、凝固角(Angle)为(50.76±9.05)°、纤维蛋白原(FIB)为(2.03±0.85)g/L、凝血酶原时间(PT)为(16.41±5.36)s、活化部分凝血酶原时间(APTT)为(42.59±17.74)s、PLTs 为(123.58±41.62)×109/L;K 值与FIB 呈负相关(P<0.05);R 值与FIB 呈负相关,与PT、APTT 呈正相关(P<0.05);MA 与FIB、PLTs 呈正相关(P<0.05);Angle 与FIB、PLTs 呈正相关(P<0.05);TEG 指导下输注血小板量、输注血浆量、输注冷沉淀量少于CCT,差异有统计学意义(P<0.05)。结论 TEG 与CCT 间具有相关性,采用TEG 检查有利于对凝血全过程进行完整、动态评估,有利于指导临床合理用血,在临床工作中可将TEG 与CCT 结合使用,对患者凝血状态进行客观准确评估,优化患者输血方案。
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谷瑞霖
关键词 血栓弹力图常规凝血试验相关性临床合理用血    
Abstract:Objective To compare the application value of thromboelastogram (TEG) and routine coagulation test (CCT)in the guidance of clinical rational blood use.Methods A total of 83 patients with indications for blood transfusion who underwent TEG and CCT in Xiamen Fifth Hospital from March 2020 to March 2021 were selected.All patients underwent TEG,CCT and blood plate count (PLTs).The TEG and CCT results and there correlation were analyzed and the application value of TEG and CCT in the guidance of clinical rational blood use were compared.Results The blood clot formation time (K) was (3.92±1.08) min,reaction time (R) was (10.58±4.16) min,maximum amplitude (MA) was (42.34±10.92) mm,α-Angle (Angle) was (50.76±9.05)°,fibrinogen (FIB) was (2.03±0.85) g/L,prothrombin time (PT) was(16.41±5.36) s,activated partial prothrombin time (APTT) was (42.59±17.74) s,PLTs was (123.58±41.62)×109/L of 83 patients.K value was negatively correlated with FIB (P<0.05).R was negatively correlated with FIB and positively correlated with PT and APTT (P<0.05).MA was positively correlated with FIB and PLTs (P<0.05).Angle was positively correlated with FIB and PLTs (P<0.05).Under the guidance of TEG,platelet volume,plasma volume and cryoprecipitate volume were less than those of CCT,and the differences were statistically significant (P<0.05).Conclusion There is a correlation between TEG and CCT.TEG examination is conducive to the complete and dynamic evaluation of the whole process of coagulation and the guidance of clinical rational blood use.In clinical work,TEG and CCT can be combined to objectively and accurately evaluate the coagulation state of patients and optimize the blood transfusion scheme of patients.
Key wordsThromboelastogram    Routine coagulation test    Correlation    Clinical rational blood use
    
引用本文:   
谷瑞霖. 血栓弹力图与常规凝血试验在临床合理用血指导中的应用价值比较[J]. 中国当代医药, 2022, 29(17): 170-172转176.
GU Ruilin. Comparison of thromboelastogram and routine coagulation test in the guidance of clinical rational blood use. 中国当代医药, 2022, 29(17): 170-172转176.
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