Abstract：Objective To investigate the efficacy of coronary CT angiography (CCTA) in predicting myocardial ischemia with Coronary plaque characteristics and stenosis. Methods From January 2019 to December 2020, 88 patients with suspected or known coronary heart disease (196 diseased vessels) admitted to Xianning First People′s Hospital were selected as the study subjects. After admission, all the enrolled patients received CCTA, coronary artery angiography(CAG)and Fractional flow reserve(FFR)examination,and the gold standard was the cardiac FFR value.According to FFR value, they were divided into ischemic group (n=45, 99 vessels with lesion, FFR value ≥0.8) and non-ischemic group(n=43, 97 vessels with lesion, FFR value <0.8). The clinical baseline data of the two groups were retrospectively analyzed, and the characteristics of CCTA plaque and the stenosis of the two groups were compared. The value of THE characteristics of CCTA plaque and the stenosis rate in the diagnosis of myocardial ischemia were analyzed. Results The degree of stenosis in the ischemic group was more severe than that in the non-ischemic group, and the difference was statistically significant (P<0.05). The results showed that the vascular plaque load, plaque volume and calcification score in the ischemic group were higher than those in the non-ischemic group, and the lesion length was lower than that in the non-ischemic group, with statistical significances (P<0.05). CT high-risk plaque and low-density plaque were more than those in the non-ischemic group, with statistical significances (P<0.05). ROC analysis showed that the AUC of CCTA lesion stenosis rate (>75% stenosis), CT high-risk plaque, lesion length and combined detection in predicting myocardial ischemia were 0.626, 0.605, 0.696 and 0.759, respectively. Conclusion CCTA has good efficacy in predicting myocardial ischemia in patients with vascular plaque characteristics and vascular stenosis rate, and the combination of CCTA and CCTA can be used as an important diagnostic index of myocardial ischemia.
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