Post-transplant lymphoproliferative disorders following renal transplantation:a case report and literatures review
LI Ying1 LIU Hang1,2▲ HAN Meng-hu3 WEI Shu-run4 ZHANG Peng1,2 BAI Bao-liang1 WANG Qian1 CHANG Yi-ge1
1.Department of Nephrology,Hebei Yanda Hospital
2.Department of Urinary Surgery,Beijing Chaoyang Hospital
3.Department of General Surgery,Hebei Yanda Hospital
4.Department of Intensive Care Unit,Hebei Yanda Hospital
Abstract:Lymphoproliferative disorders are a serious complication after solid organ or hematopoietic cell transplantation.It has low morbidity,versatile clinical manifestations and bad prognosis.At present,the understanding of this disease is still relatively limited,and there are also fewer such reports.This article reports a case of lymphoproliferative disorders after kidney transplantation and consults related literature to discuss the classification,clinical manifestations,treatment and prognosis of lymphoproliferative disorders after kidney transplantation.Through this case,it is recommended that nephrologists and urologist should pay attention to lymphoproliferative disorders after kidney transplantation and make a effective therapy.
李颖;刘航;韩猛虎;卫淑润;张鹏;白保亮;王茜;常一阁. 肾移植术后淋巴组织增生性疾病1例报道并文献复习[J]. 中国当代医药, 2020, 27(34): 221-224.
LI Ying; LIU Hang; HAN Meng-hu; WEI Shu-run; ZHANG Peng; BAI Bao-liang; WANG Qian;CHANG Yi-ge. Post-transplant lymphoproliferative disorders following renal transplantation:a case report and literatures review. 中国当代医药, 2020, 27(34): 221-224.
Hart A,Gustafson SK,Skeans MA,et al.OPTN/SRTR 2015 Annual Data Report:Early effects of the new kidney allocation system[J].Am J Transplant,2017,17 Suppl 1:543-564.
[2]
Ferreiro JF,Morscio J,Dierickx D,et al.EBV-positive and EBV-negative posttransplant diffuse large B cell lymphomas have distinct genomic and transcrip-tomic features[J].Am J Transplant,2016,16(2):414-425.
[3]
Kotton CN,Huprikar S,Kumar D.Transplant infectious diseases:a review of the scientific registry of transplant recipients published data[J].Am J Transplant,2017,17(6):1439-1446.
[4]
Swerdlow SH,Campo E,Pileri SA,et al.The 2016 revision of the World Health Organization classification of lymphoid neoplasms[J].Blood,2016,127(20):2375-2390.
Mouchli MA,Singh S,Loftus EV Jr,et al.Risk factors and outcomes of de novo cancers (excluding nonmelanoma skin cancer) after liver transplantation for primary sclerosing cholangitis[J].Transplantation,2017,101(8):1859-1866.
[8]
Mahale P,Shiels MS,Lynch CF,et al.Incidence and outcomes of primary central nervous system lymphoma in solid organ transplant recipients[J].Am J Transplant,2018,18(2):453-461.
[11]
Spagnoletti G,Salerno MP,Calia R,et al.Thymoglobuline plus basiliximab a mixed cocktail to start?[J].Transpl Immunol,2017,43-44:1-2.
[9]
Allen UD,Preiksaitis JK,AST Infectious Diseases Community of Practice.Epstein-Barr virus and posttransplant lymphoproliferative disorder in solid organ transplantation[J].Am J Transplant,2013,13 Suppl 4:107-120.
[10]
AlDabbagh MA,Gitman MR,Kumar D,et al.The role of antiviral prophylaxis for the prevention of Epstein-Barr virus-associated posttransplant lymphoproliferative disease in solid organ transplant recipients:a systematic review[J].Am J Transplant,2017,17(3):770-781.
[12]
Martinez-Calle N,Alfonso A,Rifon J,et al.First-line use of rituximab correlates with increased overall survival in late posttransplant lymphoproliferative disorders:retrospective,single-centre study[J].Eur J Haematol,2017,98(1):38-43.
[13]
Trappe RU,Dierickx D,Zimmermann H,et al.Response to Rituximab Induction Is a Predictive Marker in B-Cell Post-Transplant Lymphoproliferative Disorder and Allows Successful Stratification Into Rituximab or R-CHOP Consolidation in an International,Prospective,Multicenter PhaseⅡTrial[J].J Clin Oncol,2017,35(5):536-543.
[14]
Francis A,Johnson DW,Craig JC,et al.Incidence and predictors of cancer following kidney transplantation in childhood[J].Am J Transplant,2017,17(10):2650-2658.
[15]
Eshraghian A,Imanieh MH,Dehghani SM,et al.Posttransplant lymphoproliferative disorder after liver transplantation:Incidence,long-term survival and impact of serum tacrolimus level[J].World J Gastroenterol,2017,23(7):1224-1232.