Abstract:Objective To explore the application of Recombinant Human Endostatin Injection anti-angiogenesis combined with chemotherapy in patients with non-small cell lung cancer.Methods A total of 58 patients with non-small cell lung cancer admitted to our hospital from February 2018 to April 2019 were selected as the observation objects.The patients were randomly divided into the study group (29 cases) and the control group (29 cases).The control group was treated with conventional chemotherapy.The study group was treated with Recombinant Human Endostatin Injection anti-angiogenesis combined with chemotherapy.The total effective rate of treatment,the total effective rate of improvement of life quality and the total incidence of adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 93.10% and 55.17% in the control group,which in the study group was higher than that in the control group,with statistically significant difference (P<0.05).The total effective rate of improvement of life quality in the study group was 93.10% and 62.07% in the control group,which in the study group was higher than that in the control group,and the difference was statistically significant (P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion The application of Recombinant Human Endostatin Injection anti-angiogenesis combined with chemotherapy in the treatment of non-small cell lung cancer can effectively increase the treatment effect,improve the quality of life of patients,and has safety.
王艳茹. 重组人血管内皮抑制素注射液抗血管生成联合化疗在非小细胞肺癌患者中的应用[J]. 中国当代医药, 2020, 27(31): 100-102.
WANG Yan-ru. Application of Recombinant Human Endostatin Injection anti-angiogenesis combined with chemotherapy in patients with non-small cell lung cancer. 中国当代医药, 2020, 27(31): 100-102.
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