Abstract：Objective To explore the effect of plan-do-check action (PDCA) in prescription auditing of pharmacy intravenous admixture services (PIVAS). Methods Tracked unreasonable medical orders from 2016 to 2019, the PDCA method was used to discover the status of unreasonable medical orders, so as to analyze the reason, formulate corresponding goals and measures and continuous improvement. the reasons were analyzed, corresponding goales and measures were formulated ,then to maked continuous improvement, 2016 was before intervention, 2017 (the first round of intervention), 2018 (the second round of intervention) and 2019 (the third round of intervention) were after the implementation of the intervention. The pre-audit rate of unreasonable medical orders and the proportion of unreasonable medical orders were analyzed before and after intervention. Results After the implementation of three rounds of intervention, the pre-audit rate of unreasonable medical orders in the second and the third rounds of intervention were higher than those before intervention, the differences were statistically significant (P＜0.05). The pre-audit rate of unreasonable medical orders in the third round of intervention was higher than that in the second round, the difference was statistically significant (P＜0.05). There was no significant difference in the pre-audit rate of unreasonable medical orders between the first round of intervention and before intervention (P＞0.05). The proportion of unreasonable medical orders in the third round of intervention was lower than that before intervention, and the difference was statistically significant(P＜0.05). The second round of intervention, some proportion of unreasonable medical orders were compared with those before intervention, the differences were statistically significant (P＜0.05). There was no significant difference in the proportion of unreasonable medical orders between the first round of intervention and before intervention (P＞0.05).Conclusion PDCA circulation management can effectively promote the pre-audit rate of medical orders, reduce the proportion of unreasonable types of medical orders,and then facilitate the clinical rational use of drugs.
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