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Clinical effect of Atorvastatin combined with Aspirin in the treatment of coronary heart disease |
WANG Qi |
Department of Cardiovascula Medicine,Nanhai District People′s Hospital of Foshan City,Guangdong Province,Foshan 520200,China |
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Abstract Objective To discuss the effect of Atorvastatin combined with Aspirin in the treatment of coronary heart disease.Methods A total of 110 patients with coronary heart disease treated in our hospital from January 2018 to January 2019 were selected as the study subjects.According to the average classification method,they were divided into the control group and the observation group,with 55 cases in each group.The control group was treated with Aspirin.The observation group was treated with Atorvastatin in combination with Aspirin.The treatment effect,blood lipid levels,duration of angina pectoris,and adverse reactions were compared between the two groups.Results The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).The levels of triglyceride,serum total cholesterol and low-density lipoprotein cholesterol in the observation group were lower than those in the control group,the differences were statistically significant(P<0.05).The highdensity lipoprotein cholesterol of the observation group was higher than that of the control group after treatment,and the difference was statistically significant(P<0.05).The duration of angina pectoris in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Atorvastatin combined with Aspirin in the treatment of coronary heart disease can improve the clinical effect of patients with coronary heart disease,which is worthy of popularization and application.
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[1] |
李彦德.阿托伐他汀钙联合美托洛尔对慢性心力衰竭患者心功能、血脂水平及炎性因子的影响[J].中国现代医药杂志,2018,20(12):63-65.
|
[2] |
梁仁拔,李欣晓,黄静,等.他汀类药物在恶性肿瘤治疗中应用的进展[J].中华实用诊断与治疗杂志,2018,32(5):515-517.
|
[3] |
周立尧,郭建浩,李剑平,等.阿托伐他汀联合阿司匹林对冠心病患者血浆同型半胱氨酸、D-二聚体和脂代谢的影响[J].中国医药科学,2017,7(8):37-39.
|
[4] |
吴伟东,罗磊,易永盛,等.他汀类联合心血管药物治疗心血管疾病的临床效果分析[J].世界临床医学,2017,11(12):6,10.
|
[5] |
梁文华,王跃慧.阿托伐他汀与拜阿司匹林联合治疗方案对缺血性脑卒中患者颈动脉斑块以及疾病复发率的影响[J].山西医药杂志,2016,45(18):2147-2150.
|
[6] |
李彦德.阿托伐他汀钙联合美托洛尔对慢性心力衰竭患者心功能、血脂水平及炎性因子的影响[J].中国现代医药杂志,2018,20(12):63-65.
|
[7] |
李洋,艾丽菲热·买买提,王永涛,等.他汀类药物抵抗及其分子机制研究进展[J].中国动脉硬化杂志,2019,27(4):364-368.
|
[8] |
袁棋炎,谢金丹.阿托伐他汀联合阿司匹林治疗不稳定心绞痛的临床疗效与安全性分析[J].现代诊断与治疗,2016,27(1):73-74.
|
[9] |
都虹,郝杰,呼海娟,等.辛伐他汀增强阿司匹林对胶原诱导的血小板活化抑制作用的研究[J].中国心血管病研究,2017,15(11):1040-1043.
|
[10] |
冯娜娜,王作兰,车京津.从传统他汀及其联合治疗看调脂治疗的临床获益[J].天津医药,2018,46(2):220-224.
|
[11] |
冉宇,刘君玲,张强.他汀类和烟酸类降脂药物联合应用治疗心血管疾病[J].中国心血管杂志,2007,12(1):78-80.
|
[12] |
刘宇.不同调脂策略在心血管疾病中的研究应用进展[J].实用医院临床杂志,2019,16(3):262-265.
|
[13] |
陈锦雄,陈炳星,陈囯新,等.阿托伐他汀联合阿司匹林治疗高血压伴发动脉粥样硬化的临床研究[J].中国临床药理学杂志,2015,1(13):1236-1238.
|
[14] |
谭宝慧,刘健鹏.阿托伐他汀联合肠溶阿司匹林对短暂性脑缺血发作患者血压和血脂的影响[J].中国实验诊断学,2016,1(2):206-208.
|
[15] |
杨薇,黎小妍,钱兴国,等.磺脲类联合他汀类药物和阿司匹林对2 型糖尿病患者心血管并发症的预防作用[J].广东医学,2013,34(18):2868-2870.
|
[16] |
王欣越.调脂药物联合使用的临床策略选择[J].中国全科医学,2016,19(36):4413-4416.
|
|
|
|