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Clinical effect of Amoxicillin and Clavulanate Potassium in the treatment of urinary tract infection in children |
ZHAO Qiu-hua LIU Xiu-shu LIN Le-xin |
Department of Pediatrics,Heyuan Maternal and Child Health Care Hospital,Guangdong Province,Heyuan 517000,China |
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Abstract Objective To explore the clinical effect of Amoxicillin and Clavulanate Potassium in the treatment of urinary tract infection in children.Methods The clinical data of 118 children with urinary tract infection admitted to our hospital from September 2015 to September 2017 were retrospectively analyzed.According to the different treatment methods,they were divided into the control group and the observation group,with 59 cases in each group.Children treated with Ceftriaxone Sodium were selected as the control group,and children treated with Amoxicillin Clavulanate Potassium were selected as the observation group.The clinical treatment effect,antipyretic time,urinary bacteria turning into negative time,bacterial clearance rate and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the observation group was 96.61%,which was higher than that in the control group(84.44%),and the difference was statistically significant(P<0.05).The antipyretic time and urinary bacteria turning into negative time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The bacterial clearance rate of the observation group was 95.59%,which was higher than that of the control group (81.54%),and the difference was statistically significant(P<0.05).The total incidence rate of adverse reactions in the observation group was 5.08%,compared with 8.47%in the control group,and the difference was not statistically significant(P>0.05).Conclusion Amoxicillin and Clavulanate Potassium has a good effect in the treatment of urinary tract infection,and it can significantly shorten the healing time of children,has higher bacterial clearance rate and fewer adverse reactions,which is worthy of clinical application and promotion.
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[1] |
张蓉,龙旖,任立平等.肿瘤患者尿路感染大肠埃希菌病原菌分布及耐药性[J].中国老年学杂志,2015,(12):3329-3330.
|
[2] |
贺霞,李明伟,吕文选,等.阿莫西林克拉维酸钾治疗耐氨苄西林粪肠球菌相关性尿路感染疗效观察[J].中国实用医刊,2015,42(13):111-112.
|
[3] |
Eliakim-Raz N,Yahav D,Paul M,et al.Duration of antibiotic treatment for acute pyelonephritis and septic urinary tract infection-7 days or less versus longer treatment:systematic review and meta-analysis of randomized controlled trials[J].J Antimicrob Chemother,2013,68(10):2183-2191.
|
[4] |
张科技,刘晓艳,陈旭.截瘫患者尿路感染常见病原菌检测及耐药性分析[J].中华医院感染学杂志,2015,25(2):324-326.
|
[5] |
彭敏.小儿尿路感染的病原微生物分布及其药物敏感性试验分析[J].中国药业,2016,25(6):29-31.
|
[6] |
那彦群,叶章群,孙颖浩,等.中国泌尿外科疾病诊断治疗指南2014版[M].北京:人民卫生出版社,2013:141-142.
|
[7] |
《抗菌药物临床试验技术指导原则》写作组.抗菌药物临床试验技术指导原则[J].中国临床药理学杂志,2014,30(9):844-856.
|
[8] |
王丽琴,方拥军,金晓红,等.丹阳地区375例小儿尿路感染病原菌分布及耐药性分析[J].现代医药卫生,2017,33(20):3109-3112.
|
[9] |
范地兵,马晋.留置尿管相关尿路感染的病原菌特点及耐药性分析[J].河北医学,2016,22(2):253-256.
|
[10] |
Moltzahn F,Haeni K,Birkha user FD,et al.Peri-interventional antibiotic prophylaxis only vs continuous low-dose antibiotic treatment in patients with JJ stents:a prospective randomised trial analysing the effect on urinary tract infections and stent-related symptoms[J].BJU Int,2013,111(2):289-295.
|
[11] |
崔东岚.小儿尿路感染的微生物病原菌分布及解决对策[J].广东微量元素科学,2017,24(3):45-47.
|
[12] |
Monsen TJ,Holm SE,Ferry BM,et al.Mecillinam resistance and outcome of pivmecillinam treatment in uncomplicated lower urinary tract infection in women[J].APMIS,2014,122(4):317-323.
|
[13] |
张杰,王强,曹彩琴,等.不同输尿管支架对尿路感染患者的影响及病原学分析[J].中华医院感染学杂志,2015,25(8):1860-1862.
|
[14] |
张晓琳,赵琳娜.新生儿尿路感染临床特点及病原菌耐药趋势研究[J].世界临床医学,2016,10(4):220-221.
|
[15] |
王丽琴,方拥军,金晓红,等.丹阳地区375例小儿尿路感染病原菌分布及耐药性分析[J].现代医药卫生,2017,33(20):3109-3112.
|
|
|
|