阿替普酶静脉溶栓联合氯吡格雷、阿司匹林治疗急性ST段抬高型心肌梗死的临床效果

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Abstract Objective To observe the clinical effect of intravenous thrombolysis with Alteplase combined with Clopidogrel and Aspirin treating acute ST segment elevation myocardial infarction.Methods A total of 66 patients with acute ST-segment elevation myocardial infarction admitted into our hospital from January 2016 to January 2018 were selected.All patients were treated by intravenous thrombolysis with Alteplase combined with Clopidogrel and Aspirin.The patients were divided into the 6 h group(n=45)and＞6-12 h group(n=21)according to the time of onset.Coronary recanalization rate after treatment and APACHEⅡscore at 24 h after thrombolysis were compared in patients between the two groups.Results The coronary recanalization rate (59.09%)in the 6 h group was significantly higher than that in the＞6-12 h group(18.18%)(P＜0.05),and the APACHEⅡ score at 24 h after thrombolysis were significantly different between the two groups(P＜0.05).Conclusion intravenous thrombolysis with Alteplase combined with Clopidogrel and Aspirin treating acute ST segment elevation myocardial infarction is safe and effective treating acute ST segment elevation myocardial infarction,and the sooner thrombolysis is performed,the better the prognosis of patients.

Key words： Alteplase Clopidogrel Myocardial infarction ST segment elevation

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	Articles by authors
	YANG Xia-tong
	CHEN Ke-quan
	SU Ning
	FENG Jing-tao
	TAN Zhi-xiong
	CHEN Yang

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YANG Xia-tong,CHEN Ke-quan,SU Ning, et al. Clinical effect of intravenous thrombolysis with Alteplase combined with Clopidogrel and Aspirin treating acute ST segment elevation myocardial infarction[J]. 中国当代医药, 2018, 25(19): 161-163.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2018/V25/I19/161

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