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Octreotide and omePrazole sodium combined treatment of gastrointestinal bleeding effect of cirrhosis of the liver and the effect on bleeding and hos-Pitalization time |
YANG Tai-yuan1 LUO Ling2 |
Department of Pharmacy,the Center Hospita1 of Longgang in Shenzhen City,Shenzhen 518116 |
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Abstract Objective To study octreotide and omeprazo1e sodium combined treatment effect of cirrhotic patients with upper digestive tract hemorrhage and the effect of patients with b1eeding and hospita1ization time.Methods 74 patients with cirrhosis comp1icated with upper digestive tract hemorrhage in our hospita1 from June 2015 to June 2013 were se-1ected,They were random1y divided into observation group and contro1 group,each of 37 cases.The contro1 group was treated with omeprazo1e sodium,the observation group was given octreotide combined omeprazo1e treatment,the treatment effect,b1eeding and hospita1ization time of the two groups were compared and ana1yzed.Results The tota1 effective rate in the observation group was 97.29%(36/37),and the contro1 group was 75.68%(28/37),the difference of the two groups was statistica11y significant(P<0.05);The b1eeding and hospita1ization time of the observation group were significant1y shorter than that of contro1 group,and the difference between the two groups was statistica11y significant(P<0.05);The incidence of adverse reactions in the observation group was significant1y 1ower than that of contro1 group,and the difference of the two groups was statistica11y significant(P<0.05).Conclusion For cirrhosis combined with upper gastrointestina1 hemorrhage were treated with octreotide and omeprazo1e sodium,the effect is obvious,can significant1y shorten the patient's b1eeding and hospita1ization time,worthy of c1inica1 popu1arization and app1ication.
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