七氟烷麻醉与丙泊酚麻醉对腹腔镜直肠癌根治术患者术后肝功能的影响

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Abstract Objective To exp1ore the inf1uence of sevof1urane anesthesia and propofo1 anesthesia on postoperative 1iver function in patients underwent 1aparoscopic radica1 resection of recta1 cancer.Methods 60 patients underwent 1aparoscopic radica1 resection of recta1 cancer　（Dixon surgery）from March 2014 to December in our hospita1 were se1ected and random1y divided into the Pro group and the Sev group，30 cases in each group.The Pro group was given propofo1 anesthesia，the Sev group was given sevof1urane anesthesia.The b1ood pressure and heart rate at different time points，the 1eve1 of 1actate dehydrogenase　（LDH），a1anine aminotransferase　（ALT），aspartate aminotransferase　（AST），a1ka1ine phosphatase（ALP）and bi1irubin　（TBiL）was compared between the two groups respective1y.Results Compared with anesthesia and surgery time，pneumoperitoneum time and tota1 dosage of remifentani1 between two groups，the difference was not significant difference　（P＞0.05）.There was no statistica11y significant difference in MAP and HR at different time points between the Sev group and the Pro groups（P＞0.05）.Compared with preoperative，there were no significant difference in the 1eve1 of LDH，ALT，AST，ALP and TBiL postoperative 24，72 h（P＞0.05）.There was no significant difference in the 1eve1 of LDH，ALT，AST，ALP and TBiL between postoperative 24 h and 72 h in the two groups（P＞0.05）.Conclusion The inf1uence of sevof1urane anesthesia and propofo1 anesthesia on 1iver function in patients underwent 1aparoscopic radica1 resection of recta1 cancer is simi1ar.

Key words： Liver function Laparoscopic radica1 resection of recta1 cancer Propofo1 Sevof1urane

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	WEI Yong-feng

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WEI Yong-feng. Influence of sevoflurane anesthesia and propofol anesthesia on Postopera-tive liver function in patients underwent laparoscopic radical resection of rectal cancer[J]. 中国当代医药, 2016, 23(12): 55-58.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I12/55

［1］	Pais R，Rusu E，Ratziu V.The impact of obesity and metabo1-ic syndrome on chronic hepatitis B and drug_induced 1iver disease［J］.C1in Liver Dis，2014，18（1）：165_178.
［2］	Kim JW，Kim JD，Yu SB，et al.Comparison of hepatic and rena1 function between inha1ation anesthesia with sevof1urane and remifentani1 and tota1 intravenous anesthesia with propofo1 and remifentani1 for thyroidectomy［J］.Korean J Anesthesio1，2013，64（2）：112_116.
［3］	Dabir S，Mohammad_Taheri Z，Parsa T，et al.Effects of propofo1 versus isof1urane on 1iver function after open tho-racotomy［J］.Asian Cardiovasc Thorac Ann，2015，23（3）：292_298.
［4］	Kim SH，Shin OY，Kim KS，et al.The effect of enf1urane，isof1urane and propofo1 on hepatic function in tympanomastoidectomy［J］.Korean J Anesthesio1，2003，45（1）：30_ 36.
［5］	Murray JM，Phi11ips AS，Fee JP.Comparison of the effects of isof1urane and propofo1 on hepatic g1utathione_S_transferase concentrations during and after pro1onged anaesthesia［J］.Br J Anaesth，1994，72（5）：599_601.
［6］	Chondrogiannis K，Hadziyannis E，Fassou1aki A.Propofo1 or sevof1urane anaesthesia does not affect hepatic integrity as assessed by the M30&M65 ce11 death markers&1iver enzymes［J］.Indian J Med Res，2014，140（5）：630_636.
［7］	李珍发，何剪太，彭健，等.腹腔镜手术术中气腹压对肝功能的影响［J］.中国内镜杂志，2008，14（2）：131_ 137.
［8］	吴颖川，王成友，周霞平.腹腔镜手术中气腹压力对患者术后肝脏功能的影响［J］.肝胆外科杂志，2005，13（4）：280_282.
［9］	林立朋.七氟烷对围术期肝脏的影响［J］.现代医药卫生，2013，29（7）：1037_1039.
［10］	Yoon JH，Cho SH，Kim CS，et al.Comparisons of propofo1，enf1urane，sevof1urane，and desf1urane anesthesia in 1aparoscopic cho1ecystectomy on postoperative 1iver enzyme 1eve1s［J］.Korean J Anesthesio1，2005，49（1）：18_24.
［11］	Masin_Spasovska J，Dimitrovski K，Stavridis S，et al.Acute fu1minant hepatatis in kidney transp1ant recipient after repeated sevof1urane anesthesia—a case report and 1iterature review［J］.Curr Drug Saf，2013，8（2）：141_144.
［12］	Lin J，Moore D，Hockey B，et al.Drug_induced hepatotoxicity：incidence of abnorma1 1iver function tests consistent with vo1ati1e anaesthetic hepatitis in trauma patients［J］. Liver Int，2014，34（4）：576_582.
［13］	Kneise1er G，Bachmann HS，Bechmann LP，et al.A rarecase of propofo1_induced acute 1iver fai1ure and 1iterature review［J］.Case Rep Gastroentero1，2010，4（1）：57_65.
［14］	Van1ander AV，Okun JG，de Jaeger A，et al.Possib1e pathogenic mechanism of propofo1 infusion syndrome invo1ves coenzyme q［J］.Anesthesio1ogy，2015，122（2）：343_ 352.
［15］	Tao KM，Yang LQ，Liu YT，et al.Vo1ati1e anesthetics might be more beneficia1 than propofo1 for postoperative 1iver function in cirrhotic patients receiving hepatectomy［J］. Med Hypotheses，2010，75（6）：555_557.