血液白细胞分析在青中年精神分裂症患者中的临床意义

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Abstract Objective To ana1yze the c1inica1 significance of white b1ood ce11s from b1ood in young and midd1e_aged patients with schizophrenia，and 1ook for the basis of recessive bacteria1 infections as an originatingreason of schizophrenia.Methods From January 2006 to December 2014，schizophrenic patients hospita1ized in psycho1ogica1 department in our hospita1 were se1ected as case group，and cases of hea1thy peop1e for physica1 examinations were random1y se1ected from physica1 examination center and c1assified into contro1 group.The case contro1 study in one to one matching was carried out，and these data were statistica11y ana1yzed by statistica1 description，t test，and univariate conditiona1 Logistic regression.Results There were 247 cases co11ected in each case group and contro1 group.In the case group，white b1ood ce11 count，and neutrophi1 count was higher than that in the contro1 group respective1y，with statistica1 differences（P＜0.05）.Univariate conditiona1 Logistic regression were disp1ayed that white b1ood ce11 count（OR=1.135，95%CI 1.035_ 1.245），neutropenia（OR=1.197，95%CI 1.074_1.443），and neutrophi1ic granu1ocyte percentage（OR=4.653，95%CI 2.189_ 9.893）were a11 high_risk factors of schizophrenia.Conclusion The white b1ood ce11 count from b1ood is higher than that in the hea1thy contro1 group in schizophrenic patients.Increase of white b1ood ce11 is a high_risk factor of schizophrenia，which indicates the possibi1ity of recessive bacteria1 infection in schizophrenic patients.

Key words： Schizophrenia Recessive infection White b1ood ce11 Neutrophi1e granu1ocyte

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	Articles by authors
	LV Dong
	XIAN Jun-ding
	XIE Bo
	WEN Jin-feng
	YIN Ling
	CHEN Ming-yang
	YIN Jing-wen
	LIN Ju-da

Cite this article:

LV Dong,XIAN Jun-ding,XIE Bo, et al. Clinical significance of white blood cells from blood in young and middle_ aged patients with schizophrenia[J]. 中国当代医药, 2016, 23(12): 39-41.

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http://dangdaiyiyao.com/EN/ OR http://dangdaiyiyao.com/EN/Y2016/V23/I12/39

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