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| Clinical effect of laparoscopic minimally invasive surgery in the treatment of acute appendicitis and its influence on stress hormones and inflammatory factors |
| HU Jun-jun |
| Department of Surgery, Wuhan Seventh Hospital |
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Abstract Objective To investigate the clinical effect of laparoscopic minimally invasive surgery in the treatment of acute appendicitis and its influence on stress hormones and inflammatory factors. Methods A retrospective study of 87 patients with acute appendicitis admitted to Wuhan Seventh Hospital from June 2019 to June 2020, they were divided into laparoscopic group (45 cases) and open group (42 cases) according to the operation methods. The laparoscopic group received laparoscopic appendectomy, while the control group received open appendectomy. The perioperative indexes and postoperative complications, gastrointestinal function [gastrin (MTL) and motilin (gas)], cortisol (Cor), interleukin-6 (IL-6) and C-reactive protein (CRP) levels were compared between the two groups. Results There was no significant difference in operation time between the two groups (P＞0.05). The anal exhaust time, ambulation time and postoperative hospital stay of laparoscopic group were shorter than those of open group, the differences were statistically significant (P＜0.05). The serum levels of MLT and GAS at 3 days after operation in two groups were lower than before operation, the differences were statistically significant (P＜0.05). The total complication rate of laparoscopic group was lower than those of open group, the difference was statistically significant (P＜0.05). The levels of serum MLT and gas in laparoscopic group were higher than those in open group, the differences were statistically significant (P＜0.05). The serum levels of Cor, IL-6 and CRP in the two groups were higher than those before operation, the differences were statistically significant (P＜0.05). The serum Cor, IL-6 and CRP of laparoscopic group were lower than those of open group 3 days after operation, the differences were statistically significant (P＜0.05). Conclusion Laparoscopic appendectomy has less postoperative complications in patients with acute appendicitis, can promote the recovery of gastrointestinal function faster, and has little impact on stress-induced inflammatory response.
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| [1] |
褚忆忆.小儿急性阑尾炎治疗的研究进展[J].国际儿科学杂志，2020，47（8）：531-534.
|
| [2] |
Soliman E，Moharram A，Abdelmonem F.Reliability of the adult appendicitis score in diagnosing acute appendicitis[J].Menoufia Med J，2019，32（2）：544-548.
|
| [3] |
宛宝生，张羚术，陆启瑜，等.腹腔镜治疗老年急性阑尾炎疗效对比分析[J].中华普通外科学文献（电子版），2018，12（3）：196-199.
|
| [4] |
林俊双.腹腔镜治疗急性阑尾炎的临床效果[J].中国当代医药，2018，25（12）：36-38.
|
| [5] |
刘坤鹏，马静，邢宝平，等.腹腔镜阑尾切除术治疗急性阑尾炎的效果[J].中国临床研究，2019，32（5）：657-660.
|
| [6] |
王文卿，王磊，刘绪舜.经脐单孔腹腔镜治疗急性阑尾炎的临床效果观察[J].中国医刊，2020，55（2）：178-180.
|
| [7] |
刘欢欢，田雨，吴硕东，等.经脐单孔腹腔镜阑尾切除术治疗急性阑尾炎的应用价值及经验总结[J].中国普外基础与临床杂志，2018，25（11）：1372-1374.
|
| [8] |
黄颖初，曾格林，黎观漩.腹腔镜手术治疗小儿急性化脓性阑尾炎术后免疫、炎症水平观察[J].新医学，2018，49（10）：757-761.
|
| [9] |
龚伟，余强，程继文，等.腹腔镜手术与开腹手术治疗小儿急性化脓性阑尾炎的疗效比较[J].腹腔镜外科杂志，2018，23（6）：463-466.
|
| [10] |
周霖，熊勇，刘海燕.腹腔镜与开腹手术治疗急性阑尾炎的临床疗效及安全性比较[J].中国医药科学，2018，8（12）：219-221.
|
| [11] |
尹克宁，卓凡.单孔腹腔镜手术治疗急性阑尾炎的临床疗效[J].腹腔镜外科杂志，2018，23（2）：109-112.
|
| [12] |
杜嘉原，汪富涛.腹腔镜阑尾切除术治疗急性阑尾炎临床疗效及术后并发症研究[J].陕西医学杂志，2019，48（2）：179-182，207.
|
| [13] |
欧有冠，朱蕾，吴海燕.腹腔镜阑尾切除术与开腹手术治疗急性阑尾炎效果分析[J].中国现代普通外科进展，2019，22（8）：666.
|
| [14] |
李晓欢，周鸿鲲，梅小平，等.腹腔镜下阑尾切除术治疗穿孔性阑尾炎的疗效及对围术期氧化应激和炎症反应的影响[J].中国普通外科杂志，2018，27（3）：382-386.
|
| [15] |
杜长江.腹腔镜治疗急性阑尾炎的疗效及对血清降钙素原和C 反应蛋白水平的影响[J].中国药物与临床，2020，20（8）：1300-1302.
|
| [16] |
徐坤，吴文周，高伟，等.腹腔镜与开腹阑尾切除术对老年急性阑尾炎患者术后胃肠功能及免疫应激的影响[J].河北医药，2020，42（19）：2950-2953.
|
|
|
|
