Research progress of S100A9 and MMP-9 protein in digestive system malignant tumors
PAN Jing-gang1 XIAO Wei-dong2▲
1.Department of Hepatobiliary Surgery, People′s Hospital of Yichun City in Jiangxi Province, Yichun 336000, China;
2.Department of General Surgery, the First Affiliated Hospital of Nanchang University, Jiangxi Province, Nanchang 330006, China
Abstract：Calcium-binding proteins S100A9 is one of the important members of the S100 protein family, and matrix metalloproteinase-9 (MMP-9) is one of the most widely studied matrix metalloproteinases, which play an important role in many biological processes.Recent research suggest that S100A9 and MMP-9 play a key role in the progression of digestive system malignant tumors, and knockdown of S100A9 in cancer cells could lead to decrease the expression of MMP-9.This article will review the research progress of S100A9 and MMP-9 protein in digestive system malignant tumors.
潘井岗； 肖卫东. S100A9与基质金属蛋白酶9在消化系统恶性肿瘤中的研究进展[J]. 中国当代医药, 2019, 26(18): 19-22转27.
PAN Jing-gang； XIAO Wei-dong. Research progress of S100A9 and MMP-9 protein in digestive system malignant tumors. 中国当代医药, 2019, 26(18): 19-22转27.
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