Application evaluation of rapid on-site evaluation in endobronchial ultrasound-guided transbronchial needle aspiration
ZHANG Lei1, YE Lian-hua1, CHEN Ying1, CHEN Ya1, JIN Ping2, YANG Cheng-gang2, TAN Hui1▲
1.The First Department of Thoracic Surgery,Yunnan Cancer Hospital,Yunnan Province,Kunming 650118,China;
2.Department of Pathology,Yunnan Cancer Hospital,Yunnan Province,Kunming 650118,China
Abstract：Object To investigate the clinical value of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) combined with rapid on-site evaluation (ROSE) for enlarged hilar/mediastinal lymph nodes.Methods 104 patients with enlarged hilar/mediastinal lymph nodes by chest CT pointing out treated in Yunnan Cancer Hospital from June to December 2016 were randomly divided into the two groups,and they were given EBUS-TBNA,among them,there were 48 cases in on-site cytology group,while there were 56 cases in routine cytology group.Routine cell and histological findings were the gold standard.Results The diagnose rate in on-site cytology group and routine cytology group was 83.33% and 83.93% respectively,and the sonsistency of field cytology group with gold standard:kappa=0.883;the detection rate of malignant lymph nodes was 77.23% and 76.20% respectively,the time of puncture was (31.02±1.05) and (20.98±0.723）min respectively,the number of puncture was (1.57±0.24) times and (3.5±0.35) times,the incidence rate of puncture bleeding was 4.17%,5.37% respectively, secondary inspection rate was 0 and 3.57% respectively,and there was no statistical difference of above-mentioned data between the two groups (P>0.05).Conclusion EBUS-TBNA combined with ROSE in the diagnosis of enlarged hilar/mediastinal lymph nodes is effectively and reliable.The accuracy and gold standard is highly consistent.EBUS-TBNA combine with ROSE can reduce the incidence rate of complication such as puncture bleeding and secondary inspection rate,its safety is higher and it is better than EBUS-TBNA.
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