Abstract:ObjectiveTo investigate the preventive effect of Sodium Hyaluronate on adhesion after tendon suture and the influence of hand function.Methods74 patients with hand injuries accompanied by rupture at least 1 extensor tendons or flexor tendons from March 2014 to December 2016 in our hospital were selected as the subjects,all patients were divided into the control group (27 cases of extensor tendon,10 cases of flexor tendon)and the treatment group(27 cases of extensor tendon,10 cases of flexor tendon)according to random control and voluntary principle,37 cases in each group.The control group was treated with modified Kessler suture,and no Sodium Hyaluronate.The treatment group was treated with modified Kessler suture,and sodium hyaluronate was used to suture the tendon suture,or Sodium Hyaluronate was injected into the tendon sheath,all patients were observed and recorded in 1,2,3 months after the finger total activity(TAM),and clinical effect of the treatment of flexor tendon rupture were recorded at the same time,the complications of tendon adhesion were compared after 3 months.ResultsThe TAM of the fingers in the two groups after 1,2 and 3 months was higher than that before the treatment,with significant difference(P<0.05).The TAM of the fingers in the treatment group after 1,2 and 3 months was higher than that of the control group,with significant difference (P<0.05).The excellent and good rate of extensor tendon and flexor tendon in the treatment group after 3 months was higher than that in the control group,with significant difference(P<0.05).The adhesion rate of the treatment group was 5.40%,which was lower than 27.02%of the control group,with significant difference(P<0.05).ConclusionSodium Hyaluronate can effectively relieve tendon adhesion,promote postoperative recovery,improve the quality of life of patients,and no obvious adverse reaction,it is worthy of clinical promotion and application.
Hu J,Fan D,Lin X,et al.Safety and efficacy of Sodium Hyaluronate Gel and Chitosan in preventing postoperative peristomal adhesions after defunctioning enterostomy[J].Medicine,2015,94(51):e2354.