Clinical effect of endobronchial tube pump in the treatment of thick-wall cavity pulmonary tuberculosis
JIANG Lin LU Feiyan ZHOU Jing PENG Pinghua LAI Haibin ZENG Zhong
Department of Tuberculosis, Ganzhou Key Laboratory of Respiratory Diseases, Ganzhou Institute of Respiratory Disease Prevention and Control, the Fifth People's Hospital of Ganzhou, Jiangxi Province, Ganzhou 341000, China
Abstract：Objective To explore the clinical effect of endobronchial tube pump in the treatment of thick-wall cavity pulmonary tuberculosis. Methods A total of 60 patients with thick-wall cavity pulmonary tuberculosis admitted to the Fifth People's Hospital of Ganzhou from October 2019 to December 2020 were selected as the study objects, and they were divided into observation group and control group according to lottery method, with 30 cases in each group. The control group was treated with conventional antituberculosis chemotherapy, and the observation group was treated with endobronchial tube pump on the basis of conventional antituberculosis. The negative conversion rate of sputum tuberculosis, cavity closure rate, recurrence rate and adverse reactions were compared between the two groups. Results There was no statistically significant difference in the negative conversion rate of sputum tuberculosis between the two groups after 1 month of treatment (P＞0.05). After 2 months of treatment, the negative conversion rate of sputum tuberculosis in the observation group was higher than that in the control group, and the difference was statistically significant (P＜0.05). After 6 months of treatment, the sputum tuberculosis in the two groups turned negative, and the difference was not statistically significant (P＞0.05). After 1 month of treatment, there was no statistically significant difference in the cavity closure rate between the two groups (P＞0.05). After 2 and 6 months of treatment, the cavity closure rates of the observation group were 90.00% and 93.33%, which were higher than 43.33% and 56.67% of the control group, and the differences were statistically significant (P＜0.05). After 1 year of follow-up, there was no significant difference in the recurrence rate of thick-walled cavitary tuberculosis between the two groups (P＞0.05). There was no statistically significant difference in the total incidence of adverse reaction between the two groups (P＞0.05). Conclusion The effect of endobronchial tube pump drug in the treatment of thick-wall cavitary pulmonary tuberculosis is significant, which can promote the sputum to find tuberculosis bacteria to turn negative, improve the cavity closure rate, the recurrence rate is low, and there is no obvious adverse reaction.
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