功能性消化不良患者健康相关生命质量现状调查及其影响因素分析

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摘要目的调查功能性消化不良（FD）患者健康相关生命质量（HRQoL）现状，并分析其影响因素。方法选取2018年8月至2019年6月于北京市第六医院就诊的168 例FD 患者进行横断面研究。应用健康调查简表（SF-36）对FD 患者HRQoL 进行分析，同时调查患者临床、社会心理和人口统计因素，应用多元线性回归分析确定与FD 患者HRQoL 降低的相关因素。结果在FD 患者中，除精力（VT）外，HRQoL 各方面均有损害。躯体健康总评（PCS）评分（43.3±8.4）分，精神健康总评（MCS）评分（46.8±10.0）分。年龄增长、女性、中小学教育程度、症状严重程度是PCS 受损的影响因素（P＜0.05）。女性、症状严重程度、焦虑和抑郁是MCS 受损的影响因素（P＜0.05）。结论 FD患者HRQoL 的降低受年龄、性别、症状严重程度等因素的影响，应对这些影响因素进行积极干预，保证FD 患者的生活质量。

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	陈卫红
	李艳华
	戴宁
	张磊
	齐淑春
	王立明

关键词 ：功能性消化不良, 健康相关生命质量, 焦虑, 抑郁

Abstract：Objective To investigate the status of health-related quality of life (HRQoL) in patients with functional dyspepsia (FD) and analyze its influencing factors. Methods A total of 168 FD patients admitted to Beijing NO.6 Hospital from August 2018 to June 2019 were selected for a cross-sectional study. HRQoL of FD patients was analyzed using a brief health survey form (SF-36), and clinical, psychosocial, and demographic factors were investigated. Multiple linear regression analysis was used to determine the factors associated with decreased HRQoL in FD patients. Results In FD patients, HRQoL was impaired in all aspects except energy (VT). The total physical health assessment (PCS) score was(43.3±8.4) and the total mental health assessment (MCS) score was (46.8±10.0). Age increase, female, primary and secondary education, and severity of symptoms were the influencing factors of PCS damage (P＜0.05). Female sex, severity of symptoms, anxiety and depression were influencing factors of impaired MCS (P＜0.05). Conclusion The reduction of HRQoL in FD patients is affected by age, gender, severity of symptoms and other factors, which should be actively intervened to ensure the quality of life of FD patients.

Key words： Functional dyspepsia Health related quality of life Anxiety Depression

引用本文:

陈卫红;李艳华;戴宁;张磊;齐淑春;王立明. 功能性消化不良患者健康相关生命质量现状调查及其影响因素分析[J]. 中国当代医药, 2022, 29(9): 19-22.
CHEN Weihong;LI Yanhua;DAI Ning;ZHANG Lei;QI Shuchun;WANG Liming. Analyse of health-related quality of life in patients with functional dyspepsia and its influencing factors. 中国当代医药, 2022, 29(9): 19-22.

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