Clinical effect of Zishen Annian decoction in treatment of perimenopausal syndrome with kidney-yin deficiency
CHEN Ling-yan1，2HU Li-sha1
1.Department of Traditional Chinese Medicine,Maternal and Child Health Hospital of Jiangxi Province,Nanchang 330006,China;
2.Jiangxi Provincial Key Laboratory of Female Reproduction of Integrated Traditional Chinese and Western Medicine,Jiangxi Province,Nanchang 330006,China
Abstract：Objective To investigate the clinical effect of Zishen Annian Decoction in the treatment of perimenopausal syndrome with kidney-yin deficiency.Methods A total of 60 cases of perimenopausal syndrome with kidney yin deficiency syndrome in Maternal and Child Health Hospital of Jiangxi Province from January to October 2020 were selected as the research objects,they were divided into treatment group and control group according to the random number table method,with 30 cases in each group.The treatment group were given Zishen An′nian Decoction for 28 days,and the control group was not administered.The modified Kupperman index score and kidney-yin deficiency syndrome scores of two groups before enrollment,14 days and 28 days of enrollment were compared,and the curative effect of the treatment group was observed.Results There was no significant difference in the modified Kupperman index score between the two groups(P>0.05).The modified Kupperman index score of the treatment group at 14 and 28 d was lower than that of the control group at the same period,and the difference was statistically significant(P<0.05).There was no significant difference in the score of kidney-yin deficiency syndrome between the two groups (P>0.05).The score of kidney-yin deficiency syndrome in the treatment group was lower than that in the control group at 14 and 28 days,the difference was statistically significant(P<0.05).The total effective rate of the treatment group was 73.33%.Conclusion Zishen Annian Decoction in the treatment of perimenopausal syndrome with kidney-yin deficiency can significantly reduce the improved Kupperman score and kidney-yin deficiency syndrome scorewith good curative effect,and the therapeutic effect is related to the treatment time.
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