Abstract: Objective To analyze the pathogen infection in female reproductive tract samples from outpatients and inpatients in the First Affiliated Hospital of Fujian Medical University.Methods A total of 417 female reproductive tract pathogens nucleic acid samples were collected from outpatients and inpatients of the First Affiliated Hospital of Fujian Medical University from December 2020 to February 2021, and the nucleic acid test results and clinical data of these samples were analyzed.The pathogens include Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Mycoplasma genitalium (MG), Mycoplasma hominis (MH), herpes simplex virus typeⅡ(HSV-Ⅱ), Ureaplasma urealyticum (UU) and Ureaplasma parvum (UP), the infection status of the patient were analyzed.Results Among 417 patients, 230 (55.2%)were positive for pathogen nucleic acid.The positive rate of nucleic acid of seven pathogens was statistically significant(P<0.05), and the positive rate of UP was the highest (38.1%).There was no significant difference in the positive rate of pathogen nucleic acid among female patients of different ages (P>0.05).The positive rate of pathogen nucleic acid in patients with different clinical symptoms was significantly different (P<0.05), among which the positive rate of gynecological tumor and urinary and reproductive system infection was higher, 72.4% and 71.3%, respectively.Eighty-two women were infected with two or more pathogens at the same time, with a maximum of six pathogens at the same time.Conclusion With the continuous development of diagnostic technology, molecular diagnosis has been widely used in clinical practice, including DNA detection and RNA detection, which provide a better method for the diagnosis of these pathogens and can provide richer information for clinical diagnosis and treatment.It is necessary to pay attention to the mixed infection of common pathogens in the female reproductive system and strengthen prevention and screening.
王向荣 . 某院送检女性患者泌尿生殖道样本生殖道病原体感染情况分析[J]. 中国当代医药, 2021, 28(29): 174-177.
WANG Xiang-rong. Analysis of genitourinary tract pathogen infection of female patients in a hospital. 中国当代医药, 2021, 28(29): 174-177.