Abstract：Objective To investigate the application effect of peripherally inserted central catheter(PICC)in the concurrent chemoradiation of nasopharyngeal carcinoma patients.Methods Ninety-three nasopharyngeal carcinoma patients who underwent radiotherapy and chemotherapy in the same period from September 2015 to August 2017 were selected and divided into observation group (n=63)and control group (n=30)according to the patient′s will.The PICC was used in the observation group,and the peripheral venous indwelling needle was used in the control group.Before and 3 months after radiotherapy and chemotherapy in the same period,the quality of life of the two groups was evaluated by the EORTC QLQ-C30 questionnaire.The weight of the patients before and after treatment was recorded,and the incidence of complications of intravenous infusion during the treatment were recorded.Results Before treatment,there was no significant difference in the scores of the quality of life between the two groups(P＞0.05).In terms of the functional areas and the overall health status of the two positive indicators of quality of life,the scores after treatment in both groups were lower than before treatment.Three months after treatment,the scores of the observation group were higher than those of the control group with statistical significance (P＜0.05）.In terms of the negative quality of life index in the symptom scope,the scores of fatigue,nausea,vomiting and insomnia in the observation group were lower than those in the control group after treatment(P＜0.05）,but in terms of pain,dyspnea,constipation,diarrhea,loss of appetite and economic burden,there was no significant difference between the two groups (P＞0.05）.After treatment,the body weight of the two groups were decreased compared with those before treatment with significant differences(P＜0.05）.However,the percentage of body weight change in the observation group after treatment was higher than that in the control group with a statistical difference(P＜0.05）.After treatment,the body weight of both groups were lower than before treatment,but the weight loss in the observation group was more better than that in the control group.With regards to the incidence of complications,the incidence of phlebitis,leakage of chemical drugs,and repeated venipuncture in the observation group was lower than that in the control group with a significant difference (P＜0.05）.Conclusion The use of PICC in concurrent radiochemotherapy for nasopharyngeal carcinoma is more beneficial to the improvement of the quality of life and nutrition compared with the traditional intravenous indwelling needle and has fewer complications during infusion.
陆丹. PICC在鼻咽癌同期放化疗中的应用效果观察[J]. 中国当代医药, 2018, 25(23): 205-208.
LU Dan. Application effect observation of PICC in the concurrent chemoradiation of nasopharyngeal carcinoma. 中国当代医药, 2018, 25(23): 205-208.
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